Below are all of the organizations in South Carolina from which you can adopt a dog. Please continue on to each individual organization’s website by clicking on their name to see dogs they have available for adoption or to learn more about the organization and their mission. Adopting is a great way of bringing home a dog in need of a loving home. Consider checking with the organizations in your area on a weekly basis if you’re looking for a specific breed before you decide to go out and buy a puppy from a breeder. You know what they say – ‘Adopt Before You Shop!’
| Organization | Address | City | Phone | |
|---|---|---|---|---|
| (ARPH) Aussie Rescue & Placement Helpline | Newberry | Email Us | 877-277-4779 | |
| 4PetSake Animal Rescue | Anderson | Email Us | 864-353-2880 | |
| A Beautiful Life Animal Rescue | Simpsonville | Email Us | ||
| A Second Chance Animal Shelter, a/k/a Animal Shelter of Clarendon County | 5079 Alex Harvin Hwy | Manning | Email Us | 803-473-7075 |
| AARRFF | PO Box 911 | Mayo | Email Us | |
| Abby’s Animal Angels | Greer | Email Us | ||
| Ace’s Angels | 1997 Foxhill Rd | Lugoff | Email Us | 803-233-4388 |
| Advanced Animal Care of Mt. Pleasant | 3373 S. Morgan’s Point Rd. | Mount Pleasant | Email Us | 843-884-9838 |
| Aiken County Animal Shelter | 333 Wire Road | Aiken | N/A | 803-642-1537 |
| Airedale Rescue Group of SC | Fort Mill | Email Us | ||
| All 4 Mutz | Westminster | Email Us | 864-647-0166 | |
| All 4 Paws | 708 Petigru Drive | Pawleys Island | Email Us | 843-237-7297 |
| All For The Love Of Animals Pet Rescue Inc. | Pacolet | Email Us | ||
| Almost Home Rescue | Gaffney | Email Us | ||
| Anderson County Humane Society | P O Box 2262 | Anderson | Email Us | 864-225-9855 |
| Anderson County PAWS | 1320 Hwy 29 South | Anderson | Email Us | 864-260-4151 |
| Angel Dog Acres Rescue | 675 Liberty Church Road | Loris | Email Us | 843-877-6467 |
| Animal Advocates | 10975 Marlboro Avenue | Barnwell | N/A | 803-259-5483 |
| Animal Allies | P.O. Box 4788 | Spartanburg | Email Us | 864-576-6971 |
| Animal Angels Rescue | York | Email Us | 803-627-3049 | |
| Animal Guardians of South Carolina | PO Box 405 | Little River | Email Us | 843-283-6069 |
| Animal Lovers of Edisto Canine Rescue | Edisto Island | Email Us | 843-869-3869 | |
| Animal Perfection League | 6080 Old Leesburg Rd | Hopkins | Email Us | 803-669-2119 |
| Animal Protection League | 6080 Old Leesburg Road | Hopkins | Email Us | 803-783-2119 |
| Animal Rescue & Relief, Inc. | P.O. Box 13477 | Charleston | Email Us | 843-817-2367 |
| Animal Rescue Carolina, Inc. | P.O. Box 210668 | Columbia | Email Us | |
| Animal Rescue Fund of South Carolina | 10445 Clemson Blvd | Seneca | Email Us | 864-882-4488 |
| Animal Safe Haven | Boiling Springs | Email Us | 864-909-9249 | |
| Animal Welfare Of Laurens | P.O. Box 774 | Laurens | Email Us | 864-684-8511 |
| Animals Living Life | 2185 Ashley Phosphate Road N | N. Charleston | Email Us | 843-553-0007 |
| Ararat’s Doxie Haven | Chesnee | Email Us | 864-706-5131 | |
| Aunt Claudias Animals | 383 Stumphole Road | Elloree | Email Us | 803-826-6336 |
| Bald Is Beautiful Hairless & Small Breed Rescue | P.O. Box 8971 | Greenville | Email Us | |
| Barnwell County Animal Shelter | 55 Diamond Road, 57 Wall Street | Barnwell | Email Us | 803-259-1656 |
| Basset Rescue Crew of the Southeast | PO Box 2273 | Columbia | Email Us | 803-658-8229 |
| Beaufort County Animal Shelter and Control | PO Box 1228, Hwy. 21 | Beaufort | N/A | 843-846-3904 |
| Beaufort Humane Association | PO Box 4326 | Beaufort | Email Us | 843-757-2421 |
| Benji’s Bed and Breakfast | 295 Tiller Dr | Pawleys Island | Email Us | 843-237-7117 |
| Berkeley County P.A.W.S. | P.O. Box 903 | Goose Creek | Email Us | 843-207-7297 |
| Bird Dog Pet Rescue | Easley | Email Us | ||
| Boston Terrier Rescue of South Carolina | North Augusta | Email Us | 803-279-8069 | |
| Brighter Days Animal Rescue, Inc. | Greenville | Email Us | ||
| Brokendobe | 205 Heron Dr | Columbia | Email Us | 803-754-1098 |
| Brokendobe Doberman Rescue | Columbia/Lexington | Email Us | ||
| Bud’s Friends Animal Sanctuary | Fountain Inn | Email Us | ||
| Canine Lovers | Cayce | West Columbia | Email Us | 803-808-0875 |
| Canine Rescue | P O Box 7025 | North Augusta | Email Us | |
| Canine Rescue | P. O. Box 7025 | North Augusta | Email Us | |
| Caradobe Doberman and Feline Rescue Organization | Charleston | Email Us | 843-572-7703 | |
| CARE – Crossroads Animal Rescue | 8409 West Oak Highway | Seneca | Email Us | 864-972-9994 |
| Carmen’s Rescue | 108 Webbington Place | Simpsonville | Email Us | |
| Carolina Animal Protection Citizens Alliance | Pickens | Email Us | ||
| Carolina Basset Hound Rescue | PO Box 80082 | Charleston | Email Us | 888-909-2387 |
| Carolina Coonhound Rescue | PO Box 80223 | Charelston | Email Us | |
| Carolina German Shepherd Rescue | Leesville | Email Us | ||
| Carolina Greyhound Connection | Drayton | Email Us | 864-542-1991 | |
| Carolina Helping Paws Rescue | PO BOX 52552 | Shaw AFB | Email Us | 803-840-5205 |
| Carolina Italian Greyhound Adoption Rescue | 142 Arborgate Circle | Columbia | Email Us | 803-781-7688 |
| Carolina Loving Hound Rescue | Greenville | Email Us | ||
| Carolina Poodle Rescue | 6705 SC-18 | Pacolet | Email Us | 864-489-3559 |
| Chain Free Beaufort | PO Box 2496 | Beaufort | Email Us | 843-812-6574 |
| Chapman’s Dachshund Rescue | 1200 Chambers Rd | York | Email Us | 803-792-2473 |
| Charleston Animal Society | 2455 Remount Road | North Charleston | N/A | 843-747-4849 |
| Charleston, SC Area Great Dane Rescue | Ridgeville | Email Us | ||
| Chester County Sheriff’s Office Animal Control Division | 2714 Dawson Dr. | Chester | Email Us | 803-385-6341 |
| City of Columbia Animal Services | 127 Humane Lane (off Shop Road) | Columbia | Email Us | 803-776-7387 |
| Classic Canine, LLC | Mc Cormick | Email Us | ||
| Clinton Animal Hospital | 404 Willard Road | Clinton | Email Us | 864-833-2487 |
| Clovers Way | 111 Pinckney St | Chester | Email Us | 803-581-5586 |
| CNH Dog Rescue | 471 Hickory Nut Dr. | Inman | Email Us | 864-205-9392 |
| Coastal Animal Rescue | 1288 Limestone St | Murrelles Inlet | Email Us | 843-652-0196 |
| Coastal Jack Russell Rescue | PO Box 292 | Pawley’s Island | Email Us | 843-222-9085 |
| Colleton County Animal and Environmental Control | 33 Poor Farm Road | Walterboro | Email Us | 843-893-2651 |
| Collie Breed Rescue | Columbia | Email Us | ||
| Community Animal Shelter of Hampton | PO Box 1442, 460 Cemetery Road | Varnville | Email Us | 803-943-7567 |
| Concerned Citizens for Animals | PO Box 1332 | Simpsonville | Email Us | 864-243-4222 |
| Corgis & friends of Walmarsh | Edisto Island | Email Us | ||
| Critter Claws Rescue | Charleston | Email Us | ||
| Critter Connection | PO Box 6886 | Spartanburg | Email Us | 864-578-9226 |
| Crooked Creek Animal Rescue | Chester | Email Us | 803-374-8645 | |
| Cullen’s Archangel RescuE, Inc. | P. O. Box 715 | Lexington | Email Us | 803-622-9813 |
| Darlington County Humane Society | P.O. Box 1655 | Hartsville | Email Us | 843-398-4402 |
| Darlington County Humane Society | 1705 Harry Byrd Highway | Darlington | Email Us | |
| Diamond in the Ruff Rescue & Rehab, Inc. | Seneca | Email Us | ||
| Dillon County Animal Shelter | 1020 Old Latta Highway | Dillon | N/A | 843-841-8884 |
| Doc Williams SPCA | 502 Cypress Gardens Rd | Goose Creek | N/A | 843-761-0683 |
| Dog4U, Inc. | P.O Box 1514 | Camden | Email Us | 803-243-3773 |
| Doggone Dogs Rescue | Gaston | Email Us | 803-626-6036 | |
| DO-Good Dog Rescue | 101 Mc Dowell St | Laurens | Email Us | |
| Dot’s Place Animal Haven | Seneca | Email Us | 864-906-1443 | |
| Ela’s K9 Solutions and Rescue | Lexington | Email Us | 803-665-3406 | |
| Enoree River Rescue Inc | 14 Honeybee Lane | Taylors | Email Us | 864-268-9411 |
| Every Life Matters Animal Rescue | Rock Hill | Email Us | 803-579-1250 | |
| F.I.D.O. | Columbia | Email Us | 803-513-5524 | |
| Fairfield County Animal Adoption Center | 1678 US Hwy 321 Business N | Winnsboro | Email Us | 803-447-3602 |
| Fairfield County Animal Adoption Center | 1768 US Highway 321 Business | Winnsboro | Email Us | 803-815-0805 |
| Fairfield County Animal Shelter | 2065 US Highway 321 By-Pass North | Winnsboro | Email Us | 803-635-9944 |
| Fast Paws Haven Rescue | Westminster | Email Us | ||
| Fido Dog Rescue | West Columbia | Email Us | 803-526-0765 | |
| Florence Area Humane Society | 1007 Stockade Dr. | Florence | N/A | 843-669-2921 |
| For The Hounds | 105 Blue Ridge Dr | Clemson | Email Us | 864-654-7519 |
| Foster Paws Rescue | Greenville | Email Us | ||
| Frances R. Willis SPCA | 136 Four Paws Lane | Summerville | Email Us | 843-871-3820 |
| Freedom Fences | anderson | Email Us | ||
| Freedom Rings Rescue | P.O. Box 3664 | Sumter | Email Us | 803-565-1780 |
| Friends of Lee County Animal Shelter | 101 Animal Shelter Lane | Bishopville | Email Us | 803-428-2077 |
| Friends of Orangeburg County Animal Control | Orangeburg | Email Us | 803-534-0045 | |
| Friends of Shelter Animals Rescue & Sanctuary | P.O. Box 2851 | Lancaster | Email Us | 803-572-4482 |
| Friends of York County Animal Shelter | 713 Justice Blvd | York | Email Us | 803-628-3190 |
| Furlife German Shepherd Rescue | Charleston | Email Us | ||
| Furry Friends Rescue Center | 2775 Ranger Rd | Clover | Email Us | 803-230-3648 |
| German Shepherd Haven Rescue and Rehabilitation | Westminister | Email Us | ||
| Gold Coast Greyhoud Adoptions SC/NC | 213 Meetze Avenue | Lexington | Email Us | 803-360-3766 |
| Gold Coast Greyhound Adoptions NC | 213 Meetze Avene | Lexington | Email Us | 704-333-9862 |
| Grand Strand Golden Retriever Rescue, Inc. | P.O. Box 463 | Murrells Inlet | Email Us | 843-446-3057 |
| Grand Strand Humane Society | 3241 10th Ave. Ext. | Myrtle Beach | Email Us | 843-448-9151 |
| Grand Strand Humane Society | 3241 Mr. Joe White Avenue | Myrtle Beach | Email Us | 843-918-4910 |
| Great Dane Rescue Of South Carolina | Moncks Corner | Email Us | ||
| Greenville County Animal Care | 328 Furman Hall Road | Greenville | Email Us | 864-467-3985 |
| Greenville County Animal Care Services | 328 Furman Hall Rd | Greenville | Email Us | |
| Greenville Great Pyrenees Rescue Shelter | 100 Mill Creek Rd | Piedmont | Email Us | 864-423-9347 |
| Greenville Humane Society | 305 Airport Road | Greenville | N/A | 864-242-3626 |
| Greyhound Crossroads | PO Box 6117 | Chappells | Email Us | 864-653-6351 |
| Greyhound Crossroads | 314 Sample Road | Greenwood | Email Us | 864-995-3112 |
| Greyhound Lifesavers | 100-3 Forum Dr #150 | Columbia | Email Us | 803-414-1476 |
| Greyhound Pets of America – Charleston | PO Box 14533 | Charleston | Email Us | 843-343-2982 |
| Greyhound Pets of America – SC | Irmo | Email Us | 803-749-3174 | |
| Greyhound Pets of America South Carolina | 416 West Main Street | Lexington | Email Us | 803-732-4369 |
| Greyhounds & Love, Inc. | 5030 White City Park Road | Anderson | Email Us | 864-224-5921 |
| H. F. Help, Inc. | 202 Poplar Cir | Summerville | Email Us | 843-501-1801 |
| Hallie Hill | PO Box 508 | Ravenel | Email Us | 843-889-3713 |
| Happy Hearts, Inc. | PO Box 24 | Laurens | Email Us | 864-423-4977 |
| Hilton Head Humane Association | 10 Humane Way | Hilton Head | Email Us | 843-681-8686 |
| Holly’s Haven Pet Rescue | Simpsonville | Email Us | ||
| Homeward Bound Animal Sanctuary | 631 Azalea Patch Rd | Ruffin | Email Us | 843-866-7203 |
| Homeward Bound Pet Rescue | PO Box 4335 | Irmo | Email Us | 803-454-9094 |
| Hooves & Paws of the Upstate Rescue | Fountain Inn | Email Us | 864-327-7772 | |
| Hope Animal Rescue South Carolina | Columbia | Email Us | ||
| Horry County Animal Care Center | 1923 Industrial Park Road | Conway | Email Us | 843-915-5172 |
| Howlmore Animal Sanctuary | PO Box 61128 | Columbia | Email Us | 803-609-3888 |
| Hugs for Hounds | Simpsonville | Email Us | ||
| Hugs For Hounds – South Carolina | Simpsonville | Email Us | ||
| Humane Association of the Lowcountry | PO Box 23019 | Okatie | N/A | 843-846-8502 |
| Humane Association of the Lowcountry(HAL) | PO Box 23019 | Hilton Head Island | Email Us | |
| Humane Network Rescue | Laurens | N/A | 609-788-8050 | |
| Humane Society of Cherokee County | PO Box 2223 | Gaffney | Email Us | |
| Humane Society of Cherokee County, Inc. | P. O. Box 2223, 300 Yale Street | Gaffney | Email Us | 864-487-4769 |
| Humane Society of Greenwood | 235 Wilbanks Circle | Greenwood | Email Us | 864-942-8775 |
| Humane Society of Lancaster SC | PO Box 1825 | Lancaster | Email Us | 803-285-5683 |
| Humane Society of Marlboro | 901 Wallace Road | Bennettsville | Email Us | 843-479-3330 |
| Humane Society of McCormick County, Inc. | PO Box 900 | McCormick | Email Us | 864-391-2349 |
| Humane Society of McCormick County, Inc. | P.O. Box 900 | McCormick | Email Us | 864-828-2146 |
| Humane Society of York County | 8177 Regent Parkway | Fort Mill | Email Us | 803-802-0902 |
| Huskies R Us | Seneca | Email Us | 864-784-1466 | |
| Indian Creek Resort | 2129 Denny Hwy | Saluda | Email Us | 864-445-0355 |
| Jasper Animal Rescue Mission | 1352 Carters Mill Road | Ridgeland | Email Us | 843-726-7799 |
| Jayne H Boswell Animal Shelter/Florence Area Humane Society | 1434 McCurdy Rd | Florence | N/A | 843-629-5456 |
| Jazzy Pit Bulls Kennel and Rescue | Greenville | Email Us | ||
| k9.5 Rescue | 1754 Woodruff Rd #308 | Greenville | Email Us | 864-293-0156 |
| Kare Team Sanctuary | Longs | Email Us | 843-399-9290 | |
| Kens Corgi Acres | Iva | Email Us | 864-348-7110 | |
| Kind Keeper | 1500 LD Dr | North Myrtle Beach | Email Us | 843-855-1398 |
| L.E.A.S.H. Squad, Inc. | Graniteville | Email Us | 803-646-6204 | |
| Lancaster County Animal Shelter | 118 Kennel Lane | Lancaster | Email Us | 803-286-8103 |
| Laurens County Humane Society | 793 Poplar Street | Clinton | Email Us | 864-833-9060 |
| Leash On Life Dog Rescue | Charleston | Email Us | ||
| Lhasa APSO, Shih Tzu Rescue | spartanburg | Email Us | 864-285-4717 | |
| Licking for a Good Home Dog Rescue | PO Box 4693 | Spartanburg | Email Us | |
| Little Paws Dachshund Rescue | South Weymouth | Email Us | ||
| Little Rascals Pit Bull Rescue | Greenville | Email Us | 864-354-9385 | |
| Long Road Home Pit Bull Rescue | Sumter | Email Us | ||
| Longshot Farms Canine Protection & Rehabilitation | 913 Bethel St. Unit 1205 | Clover | Email Us | 704-675-2933 |
| Lovable Paws Rescue | 24110 Whyte Hardee Blvd | Hardeeville | Email Us | 843-422-1549 |
| Loveable Rascals Rescue | 553 Winter Drive | Cottageville | Email Us | 843-835-5773 |
| Low Country Golden Retriever Rescue Resource | P.O. Box 803 | Johns Island | Email Us | 843-571-7177 |
| Lowcountry Animal Rescue | Summerville | Email Us | ||
| Lowcountry Lab Rescue | P.O. Box 80418 | Charleston | Email Us | |
| Lowcountry Lab Rescue | PO Box 80418 | Charleston | Email Us | |
| Lowcountry Rottweiler Rescue | P.O. Box 1698 | Beaufort | Email Us | 843-592-1278 |
| Lucky Dog Rescue | P.O. Box 107 | Gaffney | Email Us | 864-804-0990 |
| Lucky Pup Rescue SC | Greenville | Email Us | ||
| LuvaPaw Animal Shelter | Hwy 14 | Greer | Email Us | |
| Make A Friend In Animals (MAFIA) | PO Box 302 | Winnsboro | Email Us | 803-606-1136 |
| Maqwas Paw Print Husky Rescue | Newberry | Email Us | 864-423-7565 | |
| Maranatha Farm | 342 Crabapple Lane | Ridgeland | Email Us | 843-816-6676 |
| Mary Ann Morris Animal Society | 254 Slow Pitch Rd. | Bamberg | Email Us | 803-245-7387 |
| Match K-9 Rescue & Rehab, Inc | Greenville | Email Us | ||
| Mercy Rescue Haven | Blacksburg | Email Us | ||
| Midlands Golden Rescue | Columbia | Email Us | 803-735-0599 | |
| Miracles with Paws | Rock Hill | Email Us | ||
| Mollys Militia | North Augusta | N/A | ||
| Mollys Militia | P. O. Box 6816 | Belvedere | Email Us | 803-279-7003 |
| Morningstar Animal Rescue & Referral, Inc. | 1626 Bees Creek Rd. | Ridgeland | Email Us | 843-684-3443 |
| Morris Animal Rescue | Winnsboro | Email Us | 803-917-7547 | |
| Mutts N’ Mugz | Charlotte | N/A | ||
| My Dog House Rescue | Richburg | Email Us | 803-374-4151 | |
| Nalley’s Nards | Liberty | Email Us | ||
| New Beginnings Shepherd Rescue | PO Box 1671 | Holly Hill | Email Us | |
| New Beginnings Shepherd Rescue | Holly Hill | Email Us | ||
| New Hope Pit Bull Rescue | PO Box 261 | Goose Creek | Email Us | |
| Newberry County Animal Care and Control | 240 Public Works Drive | Newberry | Email Us | 803-321-2185 |
| Noah’s Arks Rescue | Okatie | Email Us | 843-540-6755 | |
| Noble Ones Bully Breed Rescue | Ladson | Email Us | ||
| Noble Shepherd Rescue | PO Box 742 | Columbia | Email Us | |
| Oconee Animal Rescue, Inc. | Seneca | Email Us | 864-633-9799 | |
| Oconee Humane Society | 1925 Sandifer Blvd. | Seneca | Email Us | 864-882-4719 |
| Operation C.A.R.E. – Carolina Animal Rescue Effort | P.O. Box 10703 | Rock Hill | Email Us | |
| Operation CARE | 2756 Dr. Nichols Rd. | York | Email Us | |
| Orangeburg SPCA | 225 Ruf Rd. | Orangeburg | Email Us | 803-536-3918 |
| Out of Harm’s Way Small Dog Rescue | P.O. Box 386 | Inman | Email Us | |
| Palmetto Animal Rescue | Dillon | Email Us | ||
| Palmetto Paws Animal Rescue | Mt Pleasant | Email Us | ||
| Partners for Pets of Allendale County | 512 Hampton Avenue, P.O. Box 678 | Fairfax | N/A | 803-686-0572 |
| Patter Pets, Inc. | P.O. Box 9594 | Columbia | Email Us | 803-319-1502 |
| Pawmetto Lifeline | 1275 Bower Parkway | Columbia | Email Us | 803-465-9150 |
| Paws and Claws | 84 Huntley Shop Road | Chesterfield | Email Us | 843-378-0016 |
| PAWS Feline Rescue | Rock Hill | Email Us | ||
| Paws to the Rescue Marion County | 123 Dog & Cat Ct. | Mullins | Email Us | 843-423-8370 |
| Pawsitive Direction Spay and Neuter Assistance and Rescue Program | Sumter | Email Us | ||
| Pet Haven of SC | 28 Scarlett St | Greenville | Email Us | 864-553-3281 |
| Pet Helpers | 1447 Folly Road | Charleston | N/A | 843-795-1110 |
| Pet Tender Angels | P.O. Box 6691 | Greenville | Email Us | 864-787-2498 |
| Pets, Inc. The Carolinas Humane Society | 300 Orchard Drive | West Columbia | Email Us | 803-739-9333 |
| Phoenix Rising Border Collie Rescue of SC | 5760 Oak Hart Rd | Wadmalaw Island | Email Us | |
| Pickens County Animal Control | 181 Prison Camp Rd | Pickens | N/A | 864-898-5929 |
| Pickens County Humane Society DBA Foothills Humane | 500 Five Forks Rd | Liberty | N/A | 864-843-9693 |
| PomRescue.com Inc | P.O. Box 14 | Roebuck | Email Us | |
| PomRescue.Com, Inc. | PO Box 482 | Drayton | Email Us | |
| PTTR Rescue/Foster Home | 2979 S. Hwy 41 | Mullins | Email Us | 843-464-6532 |
| Pug Lovers Rescue/Tucker’s Way Rescue, Inc. | 1015 Charlotte Ave, Suite 170 | Rock Hill | Email Us | 803-371-5785 |
| Pups & Persians | Anderson | Email Us | ||
| Purebred Rescue of South Carolina | 141 Wilton Drive | Summerville | Email Us | |
| Purrs, Paws, and Claws | Belton | Email Us | ||
| Recycla-Bull Terrier Rescue | Columbia | Email Us | ||
| Recycled K-9 Animal Rescue | Yemassee | Email Us | ||
| Recycled Pets, Inc. | PO Box 10626 | Rock Hill | Email Us | 803-981-5087 |
| Rescue Charleston | Summerville | Email Us | ||
| Richardson Rescue | 1968 Garvin Rd. | York | Email Us | 803-684-6865 |
| Ruff Life Animal Rescue | Fort Mill | Email Us | ||
| Rural Roads Animal Rescue | Cassatt | Email Us | ||
| Russell Rescue | 52 S. Fork Rd. | Rock Hill | Email Us | 803-327-4883 |
| S.P.C.A. of Sumter | 1140 S. Guignard Drive | Sumter | Email Us | 803-773-9292 |
| Saint Frances Animal Center | 125 N. Ridge St. | Georgetown | Email Us | 843-546-0780 x 25 |
| Saint Frances Animal Center | 125 Ridge Road | Georgetown | N/A | 843-546-0780 ext 1 |
| Sandhills Chihuahua Rescue | Columbia | Email Us | ||
| Save Animals From Euthanasia | Seneca | Email Us | 864-944-2817 | |
| Save the Strays Animal Rescue | 1670-9 Springdale Drive, PMB 143 | Camden | Email Us | 843-334-8459 |
| Saved by the Heart | PO Box 774 | Greer | Email Us | 864-907-2167 |
| Second Chance K-9 Rescue of the Pee Dee | 4527 W. Belmont Circle | Florence | Email Us | 843-665-5934 |
| Shady Spot Dalmatian Rescue | Belton | Email Us | 864-230-6481 | |
| Shelter Animals Advocates | 115 Bettis Academy Rd | Graniteville | Email Us | 803-334-1219 |
| Sinbad-Sadie Second Chance Rescue | 10070 Dorchester Road, #50641 | Summerville | Email Us | 843-973-0555 |
| South Carolina Greyhound Adoption Program (SC GAP) | 414D 3rd Ave. South | Surfside Beach | Email Us | 843-828-4357 |
| South Carolina Rottweiler Rescue | Gilbert | Email Us | 803-605-5968 | |
| South Carolina Saint Bernard Rescue Foundation | 147 Harris Street | Chester | Email Us | 803-581-7402 |
| South Carolina Sheltie Rescue | Box 11414 | Columbia | Email Us | |
| South Carolina Sheltie Rescue | Columbia | Email Us | 330-321-1797 | |
| South Of The Bully Rescue | 3160 Hwy 21, Suite 103, #40 | Fort Mill | Email Us | |
| SouthEastern Keeshond Club | Travelers Rest | Email Us | ||
| Spartanburg Humane Society | 150 Dexter Road | Spartanburg | N/A | 864-583-4805 |
| SPAY Inc | Walterboro | Email Us | 843-538-6498 | |
| SPCA Albrecht Center for Animal Welfare | 199 Willow Run Road | Aiken | Email Us | 803-648-6863 |
| SQ Rescue | Columbia | N/A | ||
| SQ Rescue | Columbia | N/A | 803-223-9729 | |
| Steve’s Dog Shelter | Myrtle Beach | Email Us | 843-000-0000 | |
| Sumter Animal Control | 1240 Winkles Rd. | Sumter | N/A | 803-938-2768 |
| Sundance Mountain Animal Rescue | 170 Lewin Way | Tamassee | Email Us | |
| Sunset Animal Rescue | 405 South Congress Street | Winnsboro | Email Us | 803-635-4252 |
| Team Stinkykiss Shelter Rescue Project | North Augusta | Email Us | 803-646-2983 | |
| The Fathers House Intl – Animal Rescue Division | Westminster | Email Us | 864-647-7777 | |
| The Good Shepherd GSD Rescue | Ridgeland | Email Us | ||
| The Healing Species | P.O. Box 1202 | Orangeburg | Email Us | 803-535-6543 |
| The Heartworm Project | P.O. Box 7308 West | Columbia | Email Us | 803-394-7470 |
| The Humane Society of North Myrtle Beach, INC | 409 Bay Street North | Myrtle Beach | Email Us | 843-249-4948 |
| The Lacy Jane Foundation | The Lacy Jane Foundation | Alcolu | Email Us | 803-473-4481 |
| The Lion and the Lamb | Columbia | Email Us | ||
| The Noah Program | 1011 6th Ave. North | Surfside Beach | N/A | 843-238-1414 |
| TPC of Florence | Florence | Email Us | ||
| Union City/County Shelter | 1657 Jonesville Hwy. | Union | Email Us | 864-427-5400 |
| United Yorkie Rescue – SC – Bob and Carol Neumann | Mount Pleasant | Email Us | ||
| Upstate Animal Rescue | PO Box 195 | Townville | Email Us | |
| Upstate Animal Rescue Foundation of South Carolina | PO Box 195 | Townville | Email Us | |
| Upstate Chihuahua Rescue | Moore | Email Us | ||
| Upstate SC German Shepherd Rescue | P.O. Box 1634 | Travelers Rest | Email Us | 864-834-8842 |
| Waccamaw Animal Rescue Mission | P. O. Box 1764 | Conway | Email Us | 843-347-6583 |
| Walk by Faith Ministry | PO Box M2, 3715 Argent Blvd | Ridgeland | Email Us | 843-338-2219 |
| Walter M. Crowe Animal Shelter | 460 Fair St | Camden | Email Us | 803-425-6016 |
| Waters Edge Great Dane Rescue, Inc. | Bonneau | Email Us | ||
| Weimaraner Rescue of SC | Wagener | Email Us | ||
| Wescott Acres Pet Rescue | 6005 Wescott Rd | Columbia | Email Us | 803-732-9pet |
| Wescott Acres Pet Rescue | 6005 Wescott Rd. | Columbia | Email Us | 803-732-9738 |
| Whiskers Animal Rescue and Sanctuary | P.O. Box 70060 | Myrtle Beach | N/A | 843-455-6199 |
| Wild Heir Labrador Rescue | PO Box 81052 | Charleston | Email Us | 843-240-0174 |
| Williamsburg Animal Shelter | 205 N. Brooks Street | Kingstree | Email Us | 843-355-9312 |
| Willow’s Bend Dog Rescue, Inc. | Lancaster | Email Us | 803-288-3004 | |
| With PAHAANA | 247 Rush Lane | Camden | Email Us | 803-432-7975 |
| York County Animal Control | 713 Justice Blvd | York | Email Us | 803-818-6500 |
| Yorkie Rescue East | 1150 Hungryneck Blvd. C-369 | Mt. Pleasant | Email Us | 843-817-9263 |